Published on 19/08/202519/08/2025 by Scientist Day Dr. Xiao Sheng | Drug Development | Best Researcher Award Dr. Xiao Sheng | Naval Medical University School of Pharmacy | China Dr. Sheng Xiao, affiliated with the Navy Medical University, China, is a dedicated researcher in Biochemistry and Molecular Biology with a strong focus on intestinal stem cell biology, aging, and traditional Chinese medicine. He has led and contributed to major national and provincial projects exploring molecular mechanisms of aging, gut regeneration, and herbal medicine efficacy. With impactful publications in high-ranking journals such as Nature Communications, PLoS Biology, and Phytomedicine, Dr. Xiao has advanced understanding of intestinal injury repair, antioxidant mechanisms, and gut–brain interactions. Recognized with prestigious honors including the “Shizhen” Scholar (2025), he actively contributes to professional societies and serves on multiple editorial boards, bridging fundamental research with translational applications in medicine and nutrition. Academic Profile orcid Education Dr. Sheng Xiao received his academic training in biochemistry and molecular biology, where he built a strong foundation in molecular mechanisms underlying cellular processes, aging, and disease development. His education emphasized both traditional biochemical approaches and modern molecular biology techniques, enabling him to integrate classical knowledge with cutting-edge research in cell signaling, stem cell biology, and the therapeutic potential of natural compounds. Through this academic journey, he developed expertise in experimental design, translational medicine, and the intersection of traditional Chinese medicine with modern molecular research. Experience Dr. Xiao has established himself as a researcher at the Navy Medical University, where he has undertaken leadership roles in national and provincial research projects. He has served as a principal investigator on studies focusing on sleep disorder–related intestinal injury, nuclear lamina proteins in tumor development, and the therapeutic potential of herbal medicine. Beyond leading projects, he has actively collaborated on multidisciplinary programs supported by national funding bodies, contributing to advancements in gut regeneration, stem cell differentiation, and herbal pharmacology. His experience extends to academic service, where he contributes as an editor and active member of multiple scientific organizations, fostering international collaboration and knowledge exchange. Research Interests Dr. Xiao’s research interests span intestinal stem cell biology, aging-related diseases, molecular signaling pathways, and the therapeutic applications of traditional Chinese medicine. His work focuses on understanding how natural compounds influence gut regeneration and repair mechanisms, particularly through pathways such as Keap1–Nrf2 and srebp-mediated regulation. He also explores the molecular interactions between aging, gut health, and neurobiology through the brain–gut axis, providing insights into novel therapeutic strategies. Additionally, he integrates modern molecular biology techniques with traditional knowledge to develop innovative approaches that bridge fundamental discoveries with clinical application. Awards Dr. Xiao has received multiple recognitions for his scientific contributions, including awards for outstanding poster presentations at international congresses and national prizes in traditional Chinese medicine research forums. His achievements highlight his innovative approaches and strong impact within both basic and applied biomedical sciences. He has also been honored with distinguished scholar recognition for his excellence in research and commitment to advancing molecular biology and traditional medicine integration. These awards reflect his dedication to scientific innovation and his role as a promising leader in biomedical research. Publications Unlocking nature’s medicine cabinet through Drosophila–Driven exploration Author: Xiao Sheng, Jianzheng He, Lei Zhang Journal: Phytomedicine Year: 2025 Werner syndrome exonuclease promotes gut regeneration and causes age-associated gut hyperplasia in Drosophila Author: Kun Wu, Juanyu Zhou, Yiming Tang, Qiaoqiao Zhang, Lishou Xiong, Xiaorong Li, Zhangpeng Zhuo, Mei Luo, Yu Yuan, Xingzhu Liu, et al. Journal: PLOS Biology Year: 2025 Phase separation of BuGZ regulates gut regeneration and aging through interaction with m6A regulators Author: Qiaoqiao Zhang, Kai Deng, Mengyou Liu, Shengye Yang, Wei Xu, Tong Feng, Minwen Jie, Zhiming Liu, Xiao Sheng, Haiyang Chen, et al. Journal: Nature Communications Year: 2023 ClC‐c regulates the proliferation of intestinal stem cells via the EGFR signalling pathway in Drosophila Author: Jinping Huang, Xiao Sheng, Zhangpeng Zhuo, Danqing Xiao, Kun Wu, Gang Wan, Haiyang Chen Journal: Cell Proliferation Year: 2022 Antioxidant Effects of Caffeic Acid Lead to Protection of Drosophila Intestinal Stem Cell Aging Author: Xiao Sheng, Yuedan Zhu, Juanyu Zhou, La Yan, Gang Du, Zhiming Liu, Haiyang Chen Journal: Frontiers in Cell and Developmental Biology Year: 2021 Aging-related upregulation of the homeobox gene caudal represses intestinal stem cell differentiation in Drosophila Author: Kun Wu, Yiming Tang, Qiaoqiao Zhang, Zhangpeng Zhuo, Xiao Sheng, Jingping Huang, Jie’er Ye, Xiaorong Li, Zhiming Liu, Haiyang Chen Journal: PLOS Genetics Year: 2021 Conclusion Dr. Sheng Xiao’s groundbreaking research, leadership in prestigious projects, and commitment to advancing biochemistry and molecular biology make him an outstanding candidate. His contributions have not only deepened scientific understanding but also paved the way for innovative therapeutic applications, positioning him as a highly suitable recipient of the Best Researcher Award. Xiao Sheng | Drug Development | Best Researcher Award
Dr. Sheng Xiao, affiliated with the Navy Medical University, China, is a dedicated researcher in Biochemistry and Molecular Biology with a strong focus on intestinal stem cell biology, aging, and traditional Chinese medicine. He has led and contributed to major national and provincial projects exploring molecular mechanisms of aging, gut regeneration, and herbal medicine efficacy. With impactful publications in high-ranking journals such as Nature Communications, PLoS Biology, and Phytomedicine, Dr. Xiao has advanced understanding of intestinal injury repair, antioxidant mechanisms, and gut–brain interactions. Recognized with prestigious honors including the “Shizhen” Scholar (2025), he actively contributes to professional societies and serves on multiple editorial boards, bridging fundamental research with translational applications in medicine and nutrition. Academic Profile orcid Education Dr. Sheng Xiao received his academic training in biochemistry and molecular biology, where he built a strong foundation in molecular mechanisms underlying cellular processes, aging, and disease development. His education emphasized both traditional biochemical approaches and modern molecular biology techniques, enabling him to integrate classical knowledge with cutting-edge research in cell signaling, stem cell biology, and the therapeutic potential of natural compounds. Through this academic journey, he developed expertise in experimental design, translational medicine, and the intersection of traditional Chinese medicine with modern molecular research. Experience Dr. Xiao has established himself as a researcher at the Navy Medical University, where he has undertaken leadership roles in national and provincial research projects. He has served as a principal investigator on studies focusing on sleep disorder–related intestinal injury, nuclear lamina proteins in tumor development, and the therapeutic potential of herbal medicine. Beyond leading projects, he has actively collaborated on multidisciplinary programs supported by national funding bodies, contributing to advancements in gut regeneration, stem cell differentiation, and herbal pharmacology. His experience extends to academic service, where he contributes as an editor and active member of multiple scientific organizations, fostering international collaboration and knowledge exchange. Research Interests Dr. Xiao’s research interests span intestinal stem cell biology, aging-related diseases, molecular signaling pathways, and the therapeutic applications of traditional Chinese medicine. His work focuses on understanding how natural compounds influence gut regeneration and repair mechanisms, particularly through pathways such as Keap1–Nrf2 and srebp-mediated regulation. He also explores the molecular interactions between aging, gut health, and neurobiology through the brain–gut axis, providing insights into novel therapeutic strategies. Additionally, he integrates modern molecular biology techniques with traditional knowledge to develop innovative approaches that bridge fundamental discoveries with clinical application. Awards Dr. Xiao has received multiple recognitions for his scientific contributions, including awards for outstanding poster presentations at international congresses and national prizes in traditional Chinese medicine research forums. His achievements highlight his innovative approaches and strong impact within both basic and applied biomedical sciences. He has also been honored with distinguished scholar recognition for his excellence in research and commitment to advancing molecular biology and traditional medicine integration. These awards reflect his dedication to scientific innovation and his role as a promising leader in biomedical research. Publications Unlocking nature’s medicine cabinet through Drosophila–Driven exploration Author: Xiao Sheng, Jianzheng He, Lei Zhang Journal: Phytomedicine Year: 2025 Werner syndrome exonuclease promotes gut regeneration and causes age-associated gut hyperplasia in Drosophila Author: Kun Wu, Juanyu Zhou, Yiming Tang, Qiaoqiao Zhang, Lishou Xiong, Xiaorong Li, Zhangpeng Zhuo, Mei Luo, Yu Yuan, Xingzhu Liu, et al. Journal: PLOS Biology Year: 2025 Phase separation of BuGZ regulates gut regeneration and aging through interaction with m6A regulators Author: Qiaoqiao Zhang, Kai Deng, Mengyou Liu, Shengye Yang, Wei Xu, Tong Feng, Minwen Jie, Zhiming Liu, Xiao Sheng, Haiyang Chen, et al. Journal: Nature Communications Year: 2023 ClC‐c regulates the proliferation of intestinal stem cells via the EGFR signalling pathway in Drosophila Author: Jinping Huang, Xiao Sheng, Zhangpeng Zhuo, Danqing Xiao, Kun Wu, Gang Wan, Haiyang Chen Journal: Cell Proliferation Year: 2022 Antioxidant Effects of Caffeic Acid Lead to Protection of Drosophila Intestinal Stem Cell Aging Author: Xiao Sheng, Yuedan Zhu, Juanyu Zhou, La Yan, Gang Du, Zhiming Liu, Haiyang Chen Journal: Frontiers in Cell and Developmental Biology Year: 2021 Aging-related upregulation of the homeobox gene caudal represses intestinal stem cell differentiation in Drosophila Author: Kun Wu, Yiming Tang, Qiaoqiao Zhang, Zhangpeng Zhuo, Xiao Sheng, Jingping Huang, Jie’er Ye, Xiaorong Li, Zhiming Liu, Haiyang Chen Journal: PLOS Genetics Year: 2021 Conclusion Dr. Sheng Xiao’s groundbreaking research, leadership in prestigious projects, and commitment to advancing biochemistry and molecular biology make him an outstanding candidate. His contributions have not only deepened scientific understanding but also paved the way for innovative therapeutic applications, positioning him as a highly suitable recipient of the Best Researcher Award.
Dr. Sheng Xiao, affiliated with the Navy Medical University, China, is a dedicated researcher in Biochemistry and Molecular Biology with a strong focus on intestinal stem cell biology, aging, and traditional Chinese medicine. He has led and contributed to major national and provincial projects exploring molecular mechanisms of aging, gut regeneration, and herbal medicine efficacy. With impactful publications in high-ranking journals such as Nature Communications, PLoS Biology, and Phytomedicine, Dr. Xiao has advanced understanding of intestinal injury repair, antioxidant mechanisms, and gut–brain interactions. Recognized with prestigious honors including the “Shizhen” Scholar (2025), he actively contributes to professional societies and serves on multiple editorial boards, bridging fundamental research with translational applications in medicine and nutrition. Academic Profile orcid Education Dr. Sheng Xiao received his academic training in biochemistry and molecular biology, where he built a strong foundation in molecular mechanisms underlying cellular processes, aging, and disease development. His education emphasized both traditional biochemical approaches and modern molecular biology techniques, enabling him to integrate classical knowledge with cutting-edge research in cell signaling, stem cell biology, and the therapeutic potential of natural compounds. Through this academic journey, he developed expertise in experimental design, translational medicine, and the intersection of traditional Chinese medicine with modern molecular research. Experience Dr. Xiao has established himself as a researcher at the Navy Medical University, where he has undertaken leadership roles in national and provincial research projects. He has served as a principal investigator on studies focusing on sleep disorder–related intestinal injury, nuclear lamina proteins in tumor development, and the therapeutic potential of herbal medicine. Beyond leading projects, he has actively collaborated on multidisciplinary programs supported by national funding bodies, contributing to advancements in gut regeneration, stem cell differentiation, and herbal pharmacology. His experience extends to academic service, where he contributes as an editor and active member of multiple scientific organizations, fostering international collaboration and knowledge exchange. Research Interests Dr. Xiao’s research interests span intestinal stem cell biology, aging-related diseases, molecular signaling pathways, and the therapeutic applications of traditional Chinese medicine. His work focuses on understanding how natural compounds influence gut regeneration and repair mechanisms, particularly through pathways such as Keap1–Nrf2 and srebp-mediated regulation. He also explores the molecular interactions between aging, gut health, and neurobiology through the brain–gut axis, providing insights into novel therapeutic strategies. Additionally, he integrates modern molecular biology techniques with traditional knowledge to develop innovative approaches that bridge fundamental discoveries with clinical application. Awards Dr. Xiao has received multiple recognitions for his scientific contributions, including awards for outstanding poster presentations at international congresses and national prizes in traditional Chinese medicine research forums. His achievements highlight his innovative approaches and strong impact within both basic and applied biomedical sciences. He has also been honored with distinguished scholar recognition for his excellence in research and commitment to advancing molecular biology and traditional medicine integration. These awards reflect his dedication to scientific innovation and his role as a promising leader in biomedical research.
Publications Unlocking nature’s medicine cabinet through Drosophila–Driven exploration Author: Xiao Sheng, Jianzheng He, Lei Zhang Journal: Phytomedicine Year: 2025 Werner syndrome exonuclease promotes gut regeneration and causes age-associated gut hyperplasia in Drosophila Author: Kun Wu, Juanyu Zhou, Yiming Tang, Qiaoqiao Zhang, Lishou Xiong, Xiaorong Li, Zhangpeng Zhuo, Mei Luo, Yu Yuan, Xingzhu Liu, et al. Journal: PLOS Biology Year: 2025 Phase separation of BuGZ regulates gut regeneration and aging through interaction with m6A regulators Author: Qiaoqiao Zhang, Kai Deng, Mengyou Liu, Shengye Yang, Wei Xu, Tong Feng, Minwen Jie, Zhiming Liu, Xiao Sheng, Haiyang Chen, et al. Journal: Nature Communications Year: 2023 ClC‐c regulates the proliferation of intestinal stem cells via the EGFR signalling pathway in Drosophila Author: Jinping Huang, Xiao Sheng, Zhangpeng Zhuo, Danqing Xiao, Kun Wu, Gang Wan, Haiyang Chen Journal: Cell Proliferation Year: 2022 Antioxidant Effects of Caffeic Acid Lead to Protection of Drosophila Intestinal Stem Cell Aging Author: Xiao Sheng, Yuedan Zhu, Juanyu Zhou, La Yan, Gang Du, Zhiming Liu, Haiyang Chen Journal: Frontiers in Cell and Developmental Biology Year: 2021 Aging-related upregulation of the homeobox gene caudal represses intestinal stem cell differentiation in Drosophila Author: Kun Wu, Yiming Tang, Qiaoqiao Zhang, Zhangpeng Zhuo, Xiao Sheng, Jingping Huang, Jie’er Ye, Xiaorong Li, Zhiming Liu, Haiyang Chen Journal: PLOS Genetics Year: 2021 Conclusion Dr. Sheng Xiao’s groundbreaking research, leadership in prestigious projects, and commitment to advancing biochemistry and molecular biology make him an outstanding candidate. His contributions have not only deepened scientific understanding but also paved the way for innovative therapeutic applications, positioning him as a highly suitable recipient of the Best Researcher Award.