Shohei Katsuya | Research Excellence | Excellence in Research

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Mr. Shohei Katsuya | Research Excellence | Excellence in Research

Mr. Shohei Katsuya | Advanced Technology Laboratories, OSAKA GAS Co., Ltd. | Japan

Shohei Katsuya is a dedicated Researcher at the Advanced Technology Laboratories of OSAKA GAS Co., Ltd., where he specializes in cutting-edge metabolic and nutritional research. He holds a Master of Agriculture degree from Kyoto University, completed in March 2021, and has since been actively involved in advanced investigations centered on the physiological functions and health impacts of beta-hydroxybutyrate (BHB). Since joining Osaka Gas in April 2021, Katsuya has contributed significantly to a series of clinical and biochemical studies exploring the therapeutic potential of BHB, a key ketone body known for its roles in metabolism, energy utilization, and physiological regulation. His research focuses on understanding the metabolic pathways and physiological effects of BHB in humans, with applications ranging from obesity reduction to improved sleep quality and metabolic health. He has authored five peer-reviewed publications between 2023 and 2025 in reputable journals including Obesities, Journal of Nutritional Science and Vitaminology, Bioscience, Biotechnology, and Biochemistry, and Nutrition. These works include randomized, double-blind, placebo-controlled clinical trials investigating the effects of D-BHB on body fat reduction, sleep quality enhancement, and its safety profile in humans and animal models. Additionally, he contributed to a collaborative study demonstrating BHB’s protective effects on diabetic renal and muscular pathologies.Katsuya’s publications have collectively received 18 citations and earned an h-index of 2 according to Scopus, reflecting the emerging impact of his work within the nutritional and biochemical sciences. His ongoing projects continue to deepen scientific understanding of BHB as a functional metabolite with potential applications in health optimization, disease prevention, and metabolic regulation. Through his work, Shohei Katsuya is advancing evidence-based insights that contribute to both academic knowledge and practical applications in human health research.

Profile: Orcid

Featured Publications

Katsuya, S., Kawata, Y., Kawamura, J., Goto, T., Takara, T., & Tsubota, J. (2025). Effect of D-β-hydroxybutyric acid on body fat in Japanese adults: A randomized, double-blind, placebo-controlled study. Obesities, 5(4), 82. https://doi.org/10.3390/obesities5040082

Aisyah, R., Katsuya, S., Miyata, K., Chen, Z., Horii, M., Kudo, A., Kumrungsee, T., Tsubota, J., & Yanaka, N. (2025). β-Hydroxybutyrate attenuates diabetic renal and muscular pathologies in a streptozotocin-induced diabetic model. Nutrition, Article 112792. https://doi.org/10.1016/j.nut.2025.112792

Katsuya, S., Kawata, Y., Kawamura, Y., Kawamura, J., & Tsubota, J. (2025). Effect of d-β-hydroxybutyrate on sleep quality in healthy participants: A randomized, double-blind, placebo-controlled study. Bioscience, Biotechnology, and Biochemistry, 89(5), 769–775. https://doi.org/10.1093/bbb/zbaf017

Katsuya, S., Kawata, Y., Sugimoto, M., Nishimura, T., & Tsubota, J. (2024). Determination of the safety of Halomonas sp. KM-1-derived d-β-hydroxybutyric acid and its fermentation-derived impurities in mice and Japanese adults. Bioscience, Biotechnology, and Biochemistry, 88(9), 1073–1080. https://doi.org/10.1093/bbb/zbae088

Ip, C.-H., Higuchi, H., Wu, C.-Y., Okuda, T., Katsuya, S., Ogawa, J., & Ando, A. (2024). Production of docosahexaenoic acid by a novel isolated Aurantiochytrium sp. 6-2 using fermented defatted soybean as a nitrogen source for sustainable fish feed development. Bioscience, Biotechnology, and Biochemistry, 88(5), 872–881. https://doi.org/10.1093/bbb/zbae035

Katsuya, S., Kawata, Y., Goto, T., & Tsubota, J. (2023). Daily intake of D-β-hydroxybutyric acid (D-BHB) reduces body fat in Japanese adult participants: A randomized, double-blind, placebo-controlled study. Journal of Nutritional Science and Vitaminology, 69(2), 121–128. https://doi.org/10.3177/jnsv.69.121

gülçin gacar | Scientific Breakthroughs | Distinguished Scientist Award

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Assoc. Prof. Dr. gülçin gacar | Scientific Breakthroughs | Distinguished Scientist Award

Assoc. Prof. Dr. gülçin gacar | KOCAELI UNIVERSITY, Turkey

Dr. Gülçin Gacar is an Associate Professor at Kocaeli University, serving at the Center for Stem Cell and Gene Therapies within the Institute of Health Sciences. With a strong background in clinical microbiology, her research explores mesenchymal stem cells, exosomes, extracellular vesicles, and regenerative therapies. She actively leads and contributes to national scientific projects and serves as a mentor to graduate students. Her work bridges experimental research with clinical applications, advancing the field of stem cell biology through innovation and interdisciplinary collaboration.

Academic Profile 

ORCID, Google Scholar

Education

Dr. Gülçin Gacar pursued her academic training in medical and life sciences with a strong emphasis on clinical microbiology and cellular biology. Her foundational education equipped her with deep theoretical and practical knowledge of molecular biology, immunology, and biotechnology. Building upon this, she specialized in advanced studies of stem cells and regenerative medicine, laying the groundwork for her future research in cellular therapies and translational medicine. Her education has been a critical driver in shaping her academic vision and her interdisciplinary approach to complex biomedical challenges.

Professional Experience

Dr. Gacar currently holds the position of Associate Professor at Kocaeli University, where she is actively involved with the Center for Stem Cell and Gene Therapies. Over the years, she has gained extensive academic and research experience, having taught and mentored at undergraduate and postgraduate levels. She plays a vital role in supervising graduate theses and guiding students in advanced biomedical research. Beyond her teaching responsibilities, she is also a principal investigator and research consultant on numerous scientific projects funded by national bodies such as TÜBİTAK. Her experience includes close collaboration with multidisciplinary teams working on cellular therapies, tissue engineering, and experimental models of disease. Her leadership in research has contributed significantly to the academic output of her department and to the scientific community at large.

Research Interests

Dr. Gacar’s research focuses on the therapeutic potential of mesenchymal stem cells, exosomes, and extracellular vesicles, particularly in the context of neurodegenerative diseases, cancer biology, and tissue regeneration. Her work integrates cellular and molecular techniques to investigate disease mechanisms and therapeutic responses in experimental models. She has conducted studies on the effects of stem-cell-derived exosomes in Alzheimer’s disease models, explored the anti-inflammatory potential of compounds in oxidative stress conditions, and examined the use of photodynamic therapy agents in cancer treatment. Dr. Gacar is particularly interested in how cell-to-cell communication via extracellular vesicles can be harnessed to develop new treatment modalities. Her scientific output reflects a strong commitment to translational research, bridging the gap between bench-side discoveries and clinical applications.

Awards and Recognition

Throughout her career, Dr. Gacar has earned recognition for her contributions to medical research and scientific innovation. She has been involved in several prestigious research projects funded by national agencies, notably TÜBİTAK, and by higher education institutions. Her collaborative work has resulted in multiple successful research grants and numerous scholarly publications in peer-reviewed journals. Dr. Gacar has also contributed to the advancement of academic research infrastructure by mentoring emerging scholars and participating in advisory roles on national research panels. These accomplishments underscore her standing in the scientific community and highlight the broader impact of her research in the fields of stem cell biology and regenerative medicine.

Publications

Characterization of mesenchymal stem cells from rat bone marrow: ultrastructural properties, differentiation potential and immunophenotypic markers – Histochemistry and cell biology (2009)

Isolation and in vitro characterisation of dental pulp stem cells from natal teeth – Histochemistry and cell biology (2010)

Comparative analysis of apoptotic resistance of mesenchymal stem cells isolated from human bone marrow and adipose tissue – The Scientific World (2012)

The short-and long-term effects of estrogen deficiency on apoptosis in musculoskeletal tissues: an experimental animal model study – Archives of Iranian Medicine (2013)

In vitro protection of adipose tissue-derived mesenchymal stem cells by erythropoietin – Acta histochemica (2014)

Protective effects of resveratrol on aging-induced cognitive impairment in rats – Neurobiology of learning and memory (2016)

Restorative effect of resveratrol on expression of endothelial and neuronal nitric oxide synthase in cavernous tissues of chronic unpredictable mild stress-exposed rats: an – International Journal of Impotence Research (2018)