Diane Harper | Precision Medicine | Distinguished Scientist Award

Prof. Dr Diane Harper | Precision Medicine | Distinguished Scientist Award

Prof. Dr Diane Harper | University of MIchigan | United States

Prof. Dr. Diane M. Harper is a globally recognized physician-scientist, educator, and leader in women’s health, family medicine, and preventive oncology. She earned her SB and SM degrees in Chemical Engineering and Polymerics from the Massachusetts Institute of Technology (MIT), followed by her MD and MPH in Biostatistics/Epidemiology from the University of Kansas Medical School. Complementing her medical and public health expertise, she completed numerous prestigious postgraduate fellowships and executive leadership programs, including the Executive Leadership in Academic Medicine (ELAM) Program, University of Michigan Ross School of Business Leadership Development, and US PHS Primary Care Fellowship in Washington, D.C. Over her distinguished career, Dr. Harper has held senior academic and administrative appointments at leading institutions including Dartmouth College, University of Missouri–Kansas City, University of Louisville, and currently the University of Michigan, where she serves as a Professor of Family Medicine, Obstetrics and Gynecology, and Women’s and Gender Studies, and Affiliate Faculty in Biomedical Engineering. Her interdisciplinary expertise bridges medicine, engineering, and public health to improve women’s health outcomes worldwide. Internationally acclaimed for her pioneering work on Human Papillomavirus (HPV) and cervical cancer prevention, Dr. Harper has been instrumental in the development and clinical validation of HPV vaccines, advancing screening technologies, and establishing evidence-based guidelines for HPV-associated disease management. Her research spans clinical trials, shared decision-making, health equity, and policy reform, emphasizing underserved and physically disabled populations.

Profiles: Google Scholar

Featured Publications

Quinn, J. A., Munoz, F. M., Gonik, B., Frau, L., Cutland, C., Mallett-Moore, T., … & Harper, D. M. (2016). Preterm birth: Case definition & guidelines for data collection, analysis, and presentation of immunisation safety data. Vaccine, 34(49), 6047–6056.

Harper, D. M., DeMars, L. R. (2017). HPV vaccines – A review of the first decade. Gynecologic Oncology, 146(1), 196–204.

Tota, J. E., Struyf, F., Merikukka, M., Gonzalez, P., Kreimer, A. R., Bi, D., … & Harper, D. M. (2017). Evaluation of type replacement following HPV16/18 vaccination: pooled analysis of two randomized trials. Journal of the National Cancer Institute, 109(7), djw300.

Gorin, S. S., Jimbo, M., Heizelman, R., Harmes, K. M., & Harper, D. M. (2021). The future of cancer screening after COVID‐19 may be at home. Wiley Periodicals, Inc.

Dykens, J. A., Peterson, C. E., Holt, H. K., & Harper, D. M. (2023). Gender neutral HPV vaccination programs: Reconsidering policies to expand cancer prevention globally. Frontiers in Public Health, 11, 1067299.

gülçin gacar | Scientific Breakthroughs | Distinguished Scientist Award

Assoc. Prof. Dr. gülçin gacar | Scientific Breakthroughs | Distinguished Scientist Award

Assoc. Prof. Dr. gülçin gacar | KOCAELI UNIVERSITY, Turkey

Dr. Gülçin Gacar is an Associate Professor at Kocaeli University, serving at the Center for Stem Cell and Gene Therapies within the Institute of Health Sciences. With a strong background in clinical microbiology, her research explores mesenchymal stem cells, exosomes, extracellular vesicles, and regenerative therapies. She actively leads and contributes to national scientific projects and serves as a mentor to graduate students. Her work bridges experimental research with clinical applications, advancing the field of stem cell biology through innovation and interdisciplinary collaboration.

Academic Profile 

ORCID, Google Scholar

Education

Dr. Gülçin Gacar pursued her academic training in medical and life sciences with a strong emphasis on clinical microbiology and cellular biology. Her foundational education equipped her with deep theoretical and practical knowledge of molecular biology, immunology, and biotechnology. Building upon this, she specialized in advanced studies of stem cells and regenerative medicine, laying the groundwork for her future research in cellular therapies and translational medicine. Her education has been a critical driver in shaping her academic vision and her interdisciplinary approach to complex biomedical challenges.

Professional Experience

Dr. Gacar currently holds the position of Associate Professor at Kocaeli University, where she is actively involved with the Center for Stem Cell and Gene Therapies. Over the years, she has gained extensive academic and research experience, having taught and mentored at undergraduate and postgraduate levels. She plays a vital role in supervising graduate theses and guiding students in advanced biomedical research. Beyond her teaching responsibilities, she is also a principal investigator and research consultant on numerous scientific projects funded by national bodies such as TÜBİTAK. Her experience includes close collaboration with multidisciplinary teams working on cellular therapies, tissue engineering, and experimental models of disease. Her leadership in research has contributed significantly to the academic output of her department and to the scientific community at large.

Research Interests

Dr. Gacar’s research focuses on the therapeutic potential of mesenchymal stem cells, exosomes, and extracellular vesicles, particularly in the context of neurodegenerative diseases, cancer biology, and tissue regeneration. Her work integrates cellular and molecular techniques to investigate disease mechanisms and therapeutic responses in experimental models. She has conducted studies on the effects of stem-cell-derived exosomes in Alzheimer’s disease models, explored the anti-inflammatory potential of compounds in oxidative stress conditions, and examined the use of photodynamic therapy agents in cancer treatment. Dr. Gacar is particularly interested in how cell-to-cell communication via extracellular vesicles can be harnessed to develop new treatment modalities. Her scientific output reflects a strong commitment to translational research, bridging the gap between bench-side discoveries and clinical applications.

Awards and Recognition

Throughout her career, Dr. Gacar has earned recognition for her contributions to medical research and scientific innovation. She has been involved in several prestigious research projects funded by national agencies, notably TÜBİTAK, and by higher education institutions. Her collaborative work has resulted in multiple successful research grants and numerous scholarly publications in peer-reviewed journals. Dr. Gacar has also contributed to the advancement of academic research infrastructure by mentoring emerging scholars and participating in advisory roles on national research panels. These accomplishments underscore her standing in the scientific community and highlight the broader impact of her research in the fields of stem cell biology and regenerative medicine.

Publications

Characterization of mesenchymal stem cells from rat bone marrow: ultrastructural properties, differentiation potential and immunophenotypic markers – Histochemistry and cell biology (2009)

Isolation and in vitro characterisation of dental pulp stem cells from natal teeth – Histochemistry and cell biology (2010)

Comparative analysis of apoptotic resistance of mesenchymal stem cells isolated from human bone marrow and adipose tissue – The Scientific World (2012)

The short-and long-term effects of estrogen deficiency on apoptosis in musculoskeletal tissues: an experimental animal model study – Archives of Iranian Medicine (2013)

In vitro protection of adipose tissue-derived mesenchymal stem cells by erythropoietin – Acta histochemica (2014)

Protective effects of resveratrol on aging-induced cognitive impairment in rats – Neurobiology of learning and memory (2016)

Restorative effect of resveratrol on expression of endothelial and neuronal nitric oxide synthase in cavernous tissues of chronic unpredictable mild stress-exposed rats: an – International Journal of Impotence Research (2018)

 

 

 

Haishan Jiang | Medical Discoveries | Innovation in Science Award

Dr. Haishan Jiang | Medical Discoveries | Innovation in Science Award 

Dr. Haishan Jiang, Southern Medical University, China

Dr. Haishan Jiang, Chief Physician and Associate Professor at Southern Medical University’s Nanfang Hospital, is a leading expert in neurology, specializing in myopathy, peripheral neuropathy, and rare neurological diseases. As Deputy Director of the Neurology Department and head of the Myopathy and Peripheral Neuropathy subspecialty, he has pioneered gene therapies for SMA and ALS in South China. His research focuses on motor neuron and mitochondrial diseases, as well as gene therapy for rare conditions. Widely recognized, Dr. Jiang has been honored as the “Good Doctor of Guangzhou” and ranks top nationally in physician recommendations for multiple rare diseases.

Author Profile

ORCID

🧑‍🎓 Early Academic Pursuits

Dr. Haishan Jiang embarked on his medical journey with a deep-rooted commitment to understanding the complexities of the human nervous system. With a Doctor of Medicine degree and solid academic grounding, he demonstrated early on a keen interest in neurology, particularly in the areas of myopathy and peripheral neuropathy. His academic path was marked by diligence, a sharp scientific mind, and a profound dedication to uncovering the underlying mechanisms of rare neurological diseases. As a postgraduate supervisor, Dr. Jiang has also shown a strong passion for nurturing the next generation of medical professionals, sharing his knowledge and guiding their research pursuits with patience and precision.

🩺 Professional Endeavors

Currently serving at Nanfang Hospital of Southern Medical University, Dr. Jiang holds several key positions: Chief Physician, Associate Professor, Deputy Director of the Neurology Department, Director of Teaching, and Head of the Myopathy and Peripheral Neuropathy subspecialty. His clinical expertise spans a wide spectrum of neurological disorders, with a particular emphasis on difficult and rare conditions such as motor neuron disease (ALS), mitochondrial encephalomyopathy, and adult-onset spinal muscular atrophy (SMA). Dr. Jiang’s commitment to clinical excellence has led him to establish and lead the Guangdong Province Myopathy and Peripheral Nerve Specialized Alliance, a network aimed at advancing diagnosis, treatment, and research collaboration. Under his leadership, the department ranks among the top two nationally in terms of annual muscle and nerve biopsy volume, solidifying its reputation as a hub for neuromuscular disease care.

🧬 Contributions and Research Focus

Dr. Jiang’s research interests are firmly rooted in neurogenetic disorders, particularly motor neuron diseases (ALS) and mitochondrial disorders. His work seamlessly blends basic science with clinical application, focusing on understanding disease mechanisms and exploring cutting-edge gene therapy approaches. He has spearheaded some of South China’s most advanced gene therapy trials, including the region’s first gene therapy for adult SMA—the fourth such case in the country—and the first ALS gene therapy clinical trial in South China, also the second nationwide. His pioneering research not only contributes to academic knowledge but also offers hope to patients battling previously untreatable conditions. Through his clinical studies, Dr. Jiang is pushing the frontiers of personalized medicine, bringing precision diagnostics and therapy into the mainstream for rare and complex neurological diseases.

🏅 Accolades and Recognition

Dr. Haishan Jiang’s unwavering dedication to medical science and patient care has earned him widespread acclaim. Notably, he was honored as the sixth “Good Doctor of Guangzhou” and selected as part of the ninth batch of “Outstanding Provincial and Municipal Talents Supporting Xinjiang”, a testament to both his clinical excellence and humanitarian spirit. Furthermore, he was recognized by the Good Doctor Network as an “Annual Good Doctor” for his exceptional service in rare disease diagnosis and treatment. His reputation as a leading clinician is reflected in his top rankings in national physician recommendation lists—first place for 13 diseases, including ALS and mitochondrial encephalomyopathy, and second place for 15 others. These accolades not only highlight his expertise but also the trust he has earned from patients and peers alike.

🌍 Impact and Influence

Dr. Jiang’s work has had a transformative impact on neurology in China, particularly in the realm of rare diseases. By advancing the use of gene therapy and establishing regional alliances, he has created a robust infrastructure for collaboration, research, and clinical care. His contributions have significantly improved diagnostic timelines and therapeutic options for patients who previously faced long diagnostic odysseys and limited treatment possibilities. As a teacher and mentor, Dr. Jiang has shaped the careers of countless postgraduate students and young doctors, many of whom now contribute to clinical neurology and research across the country. His influence extends beyond the clinic to policy and advocacy, where he is a strong voice for the rare disease community.

🔬 Legacy and Future Contributions

Dr. Haishan Jiang stands at the forefront of a new era in neurology, where genomics and personalized medicine are reshaping how we understand and treat complex diseases. His legacy is already evident in the systems he has built, the patients he has helped, and the students he has inspired. Looking ahead, Dr. Jiang aims to further expand gene therapy applications, develop innovative treatment protocols, and foster international collaboration in rare disease research. With his continued focus on combining scientific rigor with compassionate care, Dr. Jiang is set to leave a lasting legacy in Chinese and global neurology. His work is not only rewriting the medical narrative for patients with rare conditions but also paving the way for future breakthroughs in neuroscience.

✍️ Publication Top Notes


📘A Multicenter Study of Hereditary Transthyretin Amyloidosis in China

Author: Xujun Chu; Juan Kang; Jingwen Xu; Haishan Jiang; Zhi‐Ying Wu; Qingping Wang; Wei Li; Jia Li;
Journal: Annals of Neurology
Year:2025

📘Knockdown of OPTN modulates miRNA-125b-5p expression via NF-κB pathways in amyotrophic lateral sclerosis

Author: Jian Qin; Ye He; Weiyi Yu; Zhaoyong Zhang; Xiaodan Chen; Yafang Hu; Haishan Jiang
Journal: Archives of Biochemistry and Biophysics
Year: 2025

📘Clinical features of hereditary transthyretin amyloidosis-polyneuropathy with transthyretin Ala97Ser(p.Ala117Ser) mutation in South Mainland China

Author: Yeli Zhu; Jingxian Fan; Xiying Zhu; Wei Li; Zhaoyong Zhang; Hui Zheng; Zhihua Zhou; Lingchao Meng; Ruxu Zhang; Haishan Jiang
Journal: Orphanet Journal of Rare Diseases
Year: 2025